A major downside to Facebook is the 5000 friend limit.It is possible however to open a number of facebooks. In a business this would preferably be done using different partners or employees.You could use the Bios for the business link in order to encourage relevant invitations from other users.
As a strategy you would join up to 30 Groups per Facebook as close to your business/product/service niche as possible and avoiding duplication. You would then invite people from those Groups to be your friends.
In one of your Facebooks you would create Groups specifically and narrowly targeted to your niche, product or service.You could even name a group the same as your product or service. You would then invite your other Facebooks to join your Groups and make them officers or administrators for your group.You would all then invite new friends to those Groups.
Do not let the Group membership exceed 5000 as you can only Direct mail your Group if the membership remains less than 5000.
Because the members have to accept the invitation anyone who joins your Group is highly qualified and a targeted lead.
Create a Page in your name or Company name, invite the other Facebooks to join and make them administrators. Then from all Facebooks invite your Friends to join this "Fan" page. There is no limit to the numbers joining your page. It is important as this is the one area of Facebook which is recognised by Google for ranking purposes.
By posting on the Wall, within the Groups and on the Page you can promote your products and services with links as often as you wish, remembering always to give lots of value to nurture trust within the Groups and Page.
Two essential applications within Facebook allow you to put an opt in box on your Profile page and on your"Fan" Page.You should always continue as your main business strategy to encourage as many targeted leads as possible to join the lists within your auto responder.